3种飞秒激光和一种角膜刀制作角膜瓣的对比研究
Comparison of laser in situ keratomileusis flaps created by 3 femtosecond lasers and a microkeratome.
J Cataract Refract Surg. 2011 Feb;37(2):349-57.
Ahn H, Kim JK, Kim CK, Han GH, Seo KY, Kim EK, Kim TI.
Source
Department of Ophthalmology, Institute of Vision Research, Yonsei University College of Medicine, Seoul, Korea.

Abstract
PURPOSE:
To evaluate the thickness and side-cut angle of laser in situ keratomileusis (LASIK) flaps created by 1 of 3 femtosecond lasers or a microkeratome using Fourier-domain optical coherence tomography (OCT).

SETTING:
Department of Ophthalmology, Institute of Vision Research, Yonsei University College of Medicine, Seoul, Korea.

DESIGN:
Comparative case series.

METHODS:
Flap creation for bilateral LASIK was performed using an IntraLase (femtosecond group 1), VisuMax (femtosecond group 2), or Femto LDV (femtosecond group 3) femtosecond laser or an M2 microkeratome. Flap thickness was determined at 14 points. The side-cut angle was measured in 4 directions at the margin interface. Measurements were taken 2 months postoperatively using an RTVue Fourier-domain OCT device and integrated software.

RESULTS:
Femtosecond group 1 comprised 50 eyes; femtosecond group 2, 40 eyes; femtosecond group 3, 64 eyes; and the microkeratome group, 52 eyes. Eyes in femtosecond groups 1 and 2 had relatively even flap configuration. Flaps in femtosecond group 3 and the microkeratome group had a meniscus shape. Flaps in femtosecond group 1 had the least difference between the mean peripheral and the central flap thickness (P<.001). The greatest flap thickness predictability (measured versus intended thickness) was in femtosecond group 3 (P<.001). Flaps in femtosecond group 1 had a side-cut angle closest to 90 degrees (P<.001).

CONCLUSIONS:
Flap morphology differed according to the system used. The 3 femtosecond laser systems appeared to be superior to the microkeratome system generally. The 3 femtosecond laser systems also produced different flap configurations depending on their individual mechanisms.

　　这项研究于2011年2月发表于白内障眼屈光杂志，该研究利用前节OCT对比分析了intralase飞秒激光，蔡司VisuMax飞秒激光，瑞士达芬奇飞秒激光和M2角膜刀制作角膜瓣的厚度和瓣缘角度。结果显示，intralase飞秒激光和蔡司VisuMax飞秒激光能够制作比较均一的角膜瓣，而瑞士达芬奇飞秒激光和M2角膜刀制作的角膜瓣为新月形（即角膜瓣中央薄边缘厚）。intralase飞秒激光制作的角膜瓣中央和边缘的厚度差异最小（即角膜瓣厚度最均一）。瑞士达芬奇飞秒激光制作角膜瓣厚度的预测性最好，而intralase飞秒激光瓣缘角度的可控性最好。
编译者注：intralase飞秒激光制瓣厚度为90μm-400μm, 以1μm增减，边切角度30-90°，以1°增减，瑞士达芬奇飞秒激只能做3个厚度90μm、110 μm、140 μm，边切角度固定28°
 　　　　　　　　　　　　　　　　　　　　　　　　　　　　　（黄正 译）